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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Juan | RF | Bayamon Predators | 27 | 03/29/2015 | Arecibo | PUR | Left | Right | 6' 1" | 200 lbs | - |
| Salas, Rafael | RP | Free Agent | 37 | 01/24/2005 | Guaynabo | PUR | Right | Right | 6' 4" | 205 lbs | - |
| Salas, Raúl | 1B | Guaynabo Commandos | 19 | 03/31/2023 | Mayagüez | PUR | Right | Right | 6' 0" | 220 lbs | - |
| Salazar, Jesús | SP | Guaynabo Commandos | 34 | 02/16/2008 | Carolina | PUR | Left | Right | 6' 3" | 200 lbs | $56,000 |
| Salazar, Jorge | C | Free Agent | 29 | 03/11/2013 | Manatí | PUR | Right | Right | 6' 0" | 200 lbs | - |
| Salazar, Luis | C | Trujillo Alto Maracas | 35 | 03/29/2007 | San Lorenzo | PUR | Right | Right | 6' 0" | 200 lbs | $274,000 |
| Salazar, Octávio | 1B | Aguadilla Roadrunners | 21 | 10/07/2021 | Dorado | PUR | Left | Left | 6' 3" | 200 lbs | - |
| Salazar, Tony | SP | San Juan Sharks | 36 | 07/06/2006 | Fajardo | PUR | Left | Right | 6' 4" | 200 lbs | $940,000 |
| Saldaña, Manny | SP | Toa Baja Gringos | 24 | 03/22/2018 | San Juan | PUR | Right | Right | 5' 9" | 170 lbs | - |
| Salgado, Albert | RP | San Juan Sharks | 27 | 01/24/2015 | San German | PUR | Right | Right | 6' 6" | 195 lbs | $188,000 |
| Salgado, José | RP | Toa Baja Gringos | 30 | 04/19/2012 | Guaynabo | PUR | Left | Left | 6' 4" | 200 lbs | $69,000 |
| Salinas, Ramiro | SP | Guaynabo Commandos | 22 | 09/22/2020 | Ceiba | PUR | Right | Right | 6' 4" | 190 lbs | - |
| Sandoval, Juan Jose | CF | Trujillo Alto Maracas | 36 | 11/25/2005 | San Juan | PUR | Right | Right | 6' 0" | 200 lbs | $710,000 |
| Sandoval, Mathew | RP | Bayamon Predators | 29 | 01/21/2013 | Bayamón | PUR | Right | Right | 6' 8" | 200 lbs | - |
| Santana, José | 2B | Guaynabo Commandos | 30 | 11/14/2011 | Río Grande | PUR | Right | Right | 6' 1" | 195 lbs | $510,000 |
| Santos, Emílio | C | San Juan Sharks | 26 | 12/27/2015 | San Juan | PUR | Right | Right | 6' 3" | 200 lbs | $30,000 |
| Santos, Félix | 3B | Free Agent | 33 | 08/29/2009 | Hormigueros | PUR | Right | Right | 6' 1" | 200 lbs | - |
| Sepúlveda, José | RP | Guaynabo Commandos | 23 | 03/08/2019 | Bayamón | PUR | Right | Right | 6' 2" | 185 lbs | - |
| Sesenta y Tres, Jose Juan | C | Bayamon Predators | 24 | 07/20/2018 | Mayagüez | PUR | Right | Right | 6' 0" | 200 lbs | $30,000 |
| Shaw, Jeremiah | RF | Free Agent | 30 | 01/14/2012 | Trujillo Alto | PUR | Left | Left | 6' 2" | 200 lbs | - |
| Shaw, Karl | 2B | Bayamon Predators | 28 | 02/08/2014 | Bayamón | PUR | Right | Right | 6' 4" | 200 lbs | $30,000 |
| Silva, Bob | C | Aguadilla Roadrunners | 21 | 06/23/2021 | Levittown | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Silva, Carlos | RP | Free Agent | 33 | 09/01/2009 | Carolina | PUR | Right | Right | 6' 4" | 200 lbs | - |
| Silva, Esteban | RP | Bayamon Predators | 23 | 03/13/2019 | Quebradillas | PUR | Left | Left | 6' 6" | 200 lbs | $30,000 |
| Silva, Foster | LF | San Juan Sharks | 21 | 02/27/2021 | San Sebastian | PUR | Right | Right | 6' 3" | 200 lbs | $30,000 |
| Silva, Juan | 1B | San Juan Sharks | 23 | 01/02/2019 | Fajardo | PUR | Left | Left | 6' 0" | 200 lbs | - |
| Silva, Roberto | 3B | Free Agent | 21 | 01/22/2021 | Bayamón | PUR | Right | Right | 6' 2" | 185 lbs | - |
| Smith, Leonard | C | Trujillo Alto Maracas | 22 | 01/18/2020 | San Juan | PUR | Right | Right | 6' 4" | 215 lbs | - |
| Snyder, Dave | RP | Guaynabo Commandos | 23 | 01/05/2019 | Ponce | PUR | Right | Right | 6' 3" | 200 lbs | - |
| Sosa, Javier | RP | San Juan Sharks | 31 | 01/09/2011 | Vega Baja | PUR | Right | Right | 6' 0" | 200 lbs | - |
| Soto, George | RP | Aguadilla Roadrunners | 21 | 05/16/2021 | Juana Díaz | PUR | Right | Right | 6' 6" | 195 lbs | - |
| Soto, Víctor | 1B | Guaynabo Commandos | 31 | 10/15/2011 | Bayamón | PUR | Right | Right | 6' 6" | 200 lbs | $1,300,000 |
| Spence, Jackson | 2B | Trujillo Alto Maracas | 30 | 02/03/2012 | Carolina | PUR | Right | Right | 6' 2" | 200 lbs | $30,000 |
| Sánchez, Beau | RP | Free Agent | 32 | 05/31/2010 | Ponce | PUR | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Carlos | 1B | San Juan Sharks | 32 | 07/15/2010 | Barceloneta | PUR | Right | Right | 6' 2" | 200 lbs | $2,960,000 |
| Sánchez, Guillermo | C | Toa Baja Gringos | 22 | 05/27/2020 | Guaynabo | PUR | Right | Right | 6' 3" | 200 lbs | $30,000 |
| Sánchez, Ramiro | 1B | Trujillo Alto Maracas | 30 | 05/10/2012 | Bayamón | PUR | Left | Left | 6' 2" | 205 lbs | $30,000 |
| Sánchez, Raúl | 2B | San Juan Sharks | 24 | 07/02/2018 | Río Grande | PUR | Right | Right | 6' 1" | 200 lbs | $30,000 |
| Sánchez, Toby | 3B | Aguadilla Roadrunners | 28 | 02/26/2014 | Carolina | PUR | Right | Right | 5' 9" | 200 lbs | $5,200,000 |
