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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Júlio Echevarría | 2035-2039 | .000 | 0 | 0 | 4 | 4 | 1 | 4.68 | 76 |
| Pat Edwards | 2015-2015 | .000 | 0 | 0 | 0 | 2 | 0 | 16.20 | 1 |
| Zander Eichhorn | 2017-2019 | .000 | 0 | 0 | 10 | 4 | 7 | 3.99 | 78 |
| John Ellis | 2012-2012 | .000 | 0 | 0 | 0 | 0 | 1 | 21.38 | 5 |
| Ed Emery | 2019-2020 | .000 | 0 | 0 | 6 | 2 | 33 | 1.94 | 146 |
| Josh Emery | 2009-2009 | .354 | 8 | 27 | 0 | 0 | 0 | 0.00 | 0 |
| António Encarnación | 2014-2014 | .143 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Ricardo Encarnación | 2039-2039 | .000 | 0 | 0 | 9 | 6 | 0 | 2.19 | 127 |
| Tomás Enríquez | 2015-2030 | .000 | 0 | 0 | 61 | 49 | 217 | 2.27 | 1080 |
| Luis Escalante | 2033-2039 | .000 | 0 | 0 | 21 | 26 | 115 | 3.23 | 275 |
| Pablo Espinosa | 2016-2026 | .280 | 0 | 151 | 0 | 0 | 0 | 0.00 | 0 |
| Tomás Espinosa | 2022-2027 | .000 | 0 | 0 | 20 | 27 | 0 | 4.45 | 269 |
| Augusto Espinoza | 2007-2014 | .000 | 0 | 0 | 31 | 33 | 2 | 4.66 | 565 |
| Octávio Estrada | 2012-2012 | .000 | 0 | 0 | 5 | 2 | 0 | 2.30 | 28 |
