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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Pedro Rodríguez# | 247 | 2028-2040 | |
| 2 | Rafael Suárez | 232 | 2011-2024 | |
| 3 | Pablo Ortíz# | 225 | 2028-2040 | |
| 4 | Chris Holmes | 217 | 2010-2026 | |
| 5 | Joe Riley# | 214 | 2031-2040 | |
| 6 | B.J. Gassaway | 177 | 2023-2034 | |
| 7 | Dave Crocker | 158 | 2018-2030 | |
| 8 | Shigekazu Shimizu | 138 | 2021-2037 | |
| 9 | Dave Hurley | 137 | 2019-2032 | |
| 10 | Carlos Garza# | 132 | 2025-2040 | |
| 10 | Leslie McDonald | 132 | 2013-2025 | |
| 12 | John Foster | 131 | 2015-2029 | |
| 12 | Joel Swedlove | 131 | 2009-2021 | |
| 14 | Nathan Carter | 129 | 2015-2026 | |
| 15 | Nikolay Rusanovsky# | 128 | 2030-2040 | |
| 16 | Jim Klein | 119 | 2018-2031 | |
| 16 | Kevin McNeill | 119 | 2007-2017 | |
| 18 | Matsusuke Hamada | 116 | 2021-2026 | |
| 19 | Logan Malone# | 115 | 2032-2040 | |
| 19 | Harley Schneider | 115 | 2023-2039 | |
| 21 | Hai-liang Choe | 104 | 2021-2036 | |
| 22 | Gil Sterling | 101 | 2017-2030 | |
| 23 | Brett Hurst | 99 | 2007-2015 | |
| 24 | Britt Martin | 95 | 2009-2018 | |
| 25 | Artie Marsh | 92 | 2007-2019 | |
| 26 | Luis Cedeño | 89 | 2021-2039 | |
| 26 | Michael Roberts# | 89 | 2034-2040 | |
| 26 | Pablo Souza | 89 | 2007-2021 | |
| 26 | Christian Webb | 89 | 2021-2039 | |
| 30 | Shuji Suzuki | 86 | 2029-2033 | |
| 31 | Theron Boswell | 84 | 2018-2027 | |
| 32 | Tony Brown | 80 | 2016-2026 | |
| 33 | Leonard Martin | 78 | 2007-2014 | |
| 33 | Juan Rincón# | 78 | 2034-2040 | |
| 35 | Rubén Ortega# | 73 | 2033-2040 | |
| 36 | Miguel Fernández# | 72 | 2034-2040 | |
| 36 | Sadaharu Harada# | 72 | 2031-2040 | |
| 38 | Glen Ganey | 71 | 2007-2018 | |
| 38 | Louis Kossan# | 71 | 2031-2040 | |
| 40 | Sixto Dueñas | 69 | 2021-2036 | |
| 40 | José González | 69 | 2011-2018 | |
| 40 | Jorge Velasco | 69 | 2012-2020 | |
| 43 | Bryan Cleveland | 67 | 2020-2036 | |
| 43 | Jason Lloyd | 67 | 2007-2011 | |
| 43 | Pedro Maldanoda | 67 | 2014-2019 | |
| 46 | Louis Crocker | 65 | 2017-2023 | |
| 46 | Esteban Rodríguez# | 65 | 2035-2040 | |
| 46 | Taylor Titmus# | 65 | 2031-2039 | |
| 49 | Alexander Craig# | 64 | 2032-2040 | |
| 49 | Mark Richardson | 64 | 2007-2017 | |
| 49 | Albert Rishworth | 64 | 2007-2016 | |
| 52 | Kaleb Felton# | 62 | 2033-2040 | |
| 53 | Steve Harris | 60 | 2011-2019 | |
| 54 | Shu-de Mu# | 58 | 2030-2040 | |
| 55 | Steve McDonald* | 57 | 2007-2020 | |
| 55 | Gilberto Valdéz | 57 | 2025-2037 | |
| 57 | Robert Robinson | 56 | 2016-2020 | |
| 58 | Yeong-hun Kim | 55 | 2021-2029 | |
| 59 | Mario Salinas | 54 | 2012-2016 | |
| 60 | Duane Higgins | 53 | 2018-2031 | |
| 60 | Min Xian | 53 | 2019-2025 | |
| 62 | Rick Coughlan# | 52 | 2026-2037 | |
| 62 | Mario Tessier | 52 | 2013-2023 | |
| 64 | Carlos Marino | 51 | 2026-2038 | |
| 64 | Colby Peña | 51 | 2025-2035 | |
| 64 | Bruce Roland | 51 | 2018-2024 | |
| 67 | Kane Chell | 49 | 2026-2032 | |
| 67 | José Gonzáles# | 49 | 2025-2037 | |
| 67 | José Lópes# | 49 | 2035-2040 | |
| 70 | Juan Carlos Gutiérrez# | 47 | 2029-2040 | |
| 70 | Raúl Medina | 47 | 2014-2028 | |
| 72 | Tenshin Kudo# | 45 | 2025-2040 | |
| 72 | Mario Sánchez | 45 | 2007-2013 | |
| 74 | George John | 44 | 2007-2017 | |
| 74 | Damon Lambert | 44 | 2014-2022 | |
| 74 | Eric Nelson# | 44 | 2036-2040 | |
| 77 | Bernardo Alvarado# | 43 | 2031-2037 | |
| 77 | Powell Clark | 43 | 2007-2013 | |
| 77 | Bryant Hawkins | 43 | 2028-2039 | |
| 80 | Alfonso Mercado | 42 | 2018-2023 | |
| 81 | Riley Cole | 41 | 2016-2022 | |
| 81 | Manny De Los Santos | 41 | 2018-2025 | |
| 83 | Roy Benthall | 40 | 2007-2012 | |
| 83 | José Escobido | 40 | 2021-2030 | |
| 83 | Ramón Leach | 40 | 2016-2027 | |
| 83 | Dave Wells | 40 | 2016-2024 | |
| 87 | Noah Hill# | 39 | 2032-2040 | |
| 87 | Joshua Ligonier | 39 | 2018-2029 | |
| 87 | Víctor Torres# | 39 | 2032-2040 | |
| 90 | Bill Jones# | 38 | 2025-2040 | |
| 91 | Nick Dunlop | 37 | 2015-2021 | |
| 91 | Armando García# | 37 | 2032-2038 | |
| 91 | Gabriel McIntyre | 37 | 2021-2037 | |
| 91 | Reuben van Driel | 37 | 2032-2036 | |
| 95 | Eugene Baker | 36 | 2019-2022 | |
| 95 | Zinedine Cozens# | 36 | 2039-2040 | |
| 95 | Alfonso Gonzáles# | 36 | 2032-2036 | |
| 95 | David Goode | 36 | 2007-2017 | |
| 99 | Gareth Bugler# | 35 | 2027-2040 | |
| 99 | Errol Landry | 35 | 2025-2033 |
