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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Xavier González | 0.804 | 2018 | |
| 2 | Gabriel Gutiérrez | 0.994 | 2017 | |
| 3 | Travis Hanson | 1.038 | 2018 | |
| 4 | Diego Perales | 1.064 | 2012 | |
| 5 | Eiichi Nakao | 1.095 | 2013 | |
| 6 | Gabriel Gutiérrez | 1.128 | 2016 | |
| 7 | Xavier González | 1.271 | 2019 | |
| 8 | Gabriel Gutiérrez | 1.298 | 2014 | |
| 9 | Ángel Valdéz | 1.323 | 2024 | |
| 10 | Xavier González | 1.369 | 2016 | |
| 11 | Gary Edwards | 1.426 | 2014 | |
| 11 | Ron Gómez# | 1.426 | 2040 | |
| 11 | Xavier González | 1.426 | 2021 | |
| 14 | José Rodríguez | 1.452 | 2030 | |
| 15 | Jorge Valentín | 1.459 | 2037 | |
| 16 | Xavier González | 1.471 | 2022 | |
| 17 | Xavier González | 1.478 | 2020 | |
| 18 | Xavier González | 1.524 | 2017 | |
| 19 | Manuel Piñal# | 1.538 | 2036 | |
| 20 | José Santos | 1.616 | 2017 | |
| 21 | Chet King | 1.645 | 2020 | |
| 22 | Ángel López# | 1.648 | 2035 | |
| 23 | Ron Gómez# | 1.650 | 2030 | |
| 24 | Manuel Piñal# | 1.678 | 2039 | |
| 25 | Javier Gómez | 1.688 | 2016 | |
| 25 | Tony Salazar# | 1.688 | 2038 | |
| 27 | Ángel Valdéz | 1.707 | 2025 | |
| 28 | Alberto Caballero# | 1.729 | 2039 | |
| 29 | Gustavo Luján# | 1.737 | 2035 | |
| 30 | Miguel Cordero# | 1.745 | 2035 | |
| 31 | Pedro Ramírez# | 1.746 | 2039 | |
| 32 | Carlton Minor# | 1.761 | 2039 | |
| 33 | Joe Rivera | 1.790 | 2035 | |
| 34 | Gabriel Gutiérrez | 1.794 | 2019 | |
| 35 | Javier Gómez | 1.805 | 2017 | |
| 36 | Juan Gonzáles | 1.826 | 2027 | |
| 37 | Juan Martínez | 1.849 | 2014 | |
| 37 | Walt Porter# | 1.849 | 2031 | |
| 39 | Tomás Esparza | 1.856 | 2033 | |
| 40 | José Santos | 1.857 | 2025 | |
| 41 | Ron Gómez# | 1.862 | 2033 | |
| 42 | Humberto Hernández# | 1.892 | 2036 | |
| 43 | José Santos | 1.893 | 2021 | |
| 44 | Tomás Esparza | 1.896 | 2027 | |
| 45 | Kirby Gibson | 1.901 | 2014 | |
| 46 | Gabriel Gutiérrez | 1.919 | 2013 | |
| 47 | José Santos | 1.929 | 2023 | |
| 48 | José Morín | 1.935 | 2018 | |
| 49 | Ron Gómez# | 1.953 | 2029 | |
| 50 | Gabriel Gutiérrez | 1.960 | 2018 | |
| 51 | José Santos | 1.966 | 2014 | |
| 52 | Javier Gómez | 1.967 | 2018 | |
| 53 | Orlando Ruíz# | 2.015 | 2038 | |
| 54 | Gabriel Gutiérrez | 2.019 | 2020 | |
| 55 | José Rodríguez | 2.023 | 2028 | |
| 56 | Jerry Collins | 2.027 | 2015 | |
| 57 | Pedro Concepción | 2.031 | 2018 | |
| 58 | Ángel Valdéz | 2.063 | 2020 | |
| 59 | Jesús Salazar# | 2.064 | 2037 | |
| 60 | Zander Eichhorn | 2.077 | 2016 | |
| 60 | Jay Black# | 2.077 | 2041 | |
| 62 | Clark Vallés# | 2.084 | 2034 | |
| 63 | Gustavo Luján# | 2.090 | 2039 | |
| 64 | Juan Alvarado | 2.092 | 2029 | |
| 65 | Ken Martínez# | 2.096 | 2040 | |
| 66 | Juan Alvarado | 2.101 | 2031 | |
| 67 | José López | 2.106 | 2017 | |
| 68 | Clark Vallés# | 2.112 | 2033 | |
| 69 | Martín Martínez# | 2.124 | 2033 | |
| 70 | Eiichi Nakao | 2.129 | 2017 | |
| 71 | Miguel Cordero# | 2.132 | 2040 | |
| 72 | José Morín | 2.144 | 2017 | |
| 73 | Jorge Alou | 2.163 | 2029 | |
| 74 | Fred Negrón | 2.172 | 2014 | |
| 75 | Ken Martínez# | 2.176 | 2034 | |
| 76 | Carlton Minor# | 2.194 | 2036 | |
| 77 | Ron Gómez# | 2.201 | 2038 | |
| 78 | Tomás Esparza | 2.209 | 2016 | |
| 78 | Eiichi Nakao | 2.209 | 2012 | |
| 80 | Arturo Ramírez | 2.215 | 2022 | |
| 81 | Carlton Minor# | 2.234 | 2041 | |
| 82 | Pedro Ramírez | 2.236 | 2010 | |
| 83 | Miguel Cordero# | 2.237 | 2033 | |
| 84 | Jorge Valentín | 2.238 | 2033 | |
| 85 | Gustavo Luján# | 2.257 | 2034 | |
| 86 | Arturo Ramírez | 2.258 | 2024 | |
| 87 | Miguel Cordero# | 2.263 | 2039 | |
| 88 | Ron Gómez# | 2.271 | 2039 | |
| 89 | Martin Rodríguez# | 2.276 | 2039 | |
| 90 | José Santos | 2.282 | 2016 | |
| 91 | Emílio Alvarado | 2.285 | 2007 | |
| 92 | Arturo Ramírez | 2.295 | 2025 | |
| 93 | Clark Vallés# | 2.307 | 2037 | |
| 94 | Iván Rosa | 2.311 | 2031 | |
| 95 | Miguel Cordero# | 2.330 | 2036 | |
| 96 | Domingo Pérez# | 2.339 | 2036 | |
| 97 | Jay Black# | 2.348 | 2035 | |
| 98 | José Morín | 2.356 | 2019 | |
| 99 | Tomás Esparza | 2.362 | 2018 | |
| 100 | Eduardo Camacho# | 2.366 | 2039 |
