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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Tony Carmona | 133 | 2007-2015 | |
| 2 | Carlos Aguilera | 81 | 2020-2027 | |
| 3 | José Aquino# | 37 | 2034-2041 | |
| 4 | Rafael Delgado# | 29 | 2034-2041 | |
| 5 | Ramón Estrada | 27 | 2007-2020 | |
| 6 | Júlio Gonzáles# | 23 | 2031-2041 | |
| 7 | César Tirado | 17 | 2015-2023 | |
| 8 | Luis Salazar# | 16 | 2035-2041 | |
| 9 | Juan Méndez# | 10 | 2036-2041 | |
| 10 | Jesús Méndez | 8 | 2018-2020 | |
| 11 | Gustavo Gonzáles# | 7 | 2038-2041 | |
| 11 | Kuniaki Ohayashi | 7 | 2007-2010 | |
| 13 | Jesús Prieto | 6 | 2015-2015 | |
| 13 | John Ray | 6 | 2014-2015 | |
| 13 | Xavier Vázquez | 6 | 2007-2013 | |
| 16 | José Castillo | 5 | 2015-2019 | |
| 16 | Pedro Rojas | 5 | 2007-2012 | |
| 18 | Luis Arteaga# | 4 | 2036-2041 | |
| 18 | Ricardo Cortéz | 4 | 2007-2012 | |
| 20 | Luis Pereira# | 3 | 2036-2041 | |
| 20 | Jaime Rodríguez# | 3 | 2039-2040 | |
| 22 | Ernesto Alicea | 2 | 2012-2013 | |
| 22 | Enrico Díaz# | 2 | 2041-2041 | |
| 22 | Félix Lima | 2 | 2020-2023 | |
| 22 | Emílio Santos# | 2 | 2037-2041 | |
| 22 | Marvin Walters | 2 | 2008-2008 | |
| 22 | Jerry Williams# | 2 | 2040-2040 | |
| 28 | Juan Jose Benítez | 1 | 2014-2015 | |
| 28 | Nathan Clark | 1 | 2014-2014 | |
| 28 | Juan Garza# | 1 | 2036-2041 | |
| 28 | Ángelo González | 1 | 2013-2013 | |
| 28 | Alfredo Gutiérrez | 1 | 2007-2012 | |
| 28 | Warren Johnson# | 1 | 2038-2040 | |
| 28 | Manuel López# | 1 | 2040-2041 | |
| 28 | Augusto Spindola | 1 | 2014-2015 | |
| 28 | Guillermo Sánchez# | 1 | 2040-2041 | |
| 37 | Jesús Chapa# | 0 | 2041-2041 | |
| 37 | Félix Chávez# | 0 | 2041-2041 | |
| 37 | Francisco Dávila# | 0 | 2034-2040 | |
| 37 | John Hendershot | 0 | 2014-2014 | |
| 37 | Toyozo Ishihara | 0 | 2007-2007 | |
| 37 | Tanyu Kobayashi | 0 | 2008-2008 | |
| 37 | Douglas McEvoy | 0 | 2011-2011 | |
| 37 | Eduardo Medina# | 0 | 2041-2041 | |
| 37 | Iván Peña# | 0 | 2035-2035 | |
| 37 | António Reyes | 0 | 2011-2011 | |
| 37 | Donnie Tillman# | 0 | 2041-2041 | |
| 37 | Pablo Vélez | 0 | 2014-2014 |
