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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Luis Ramos | 12 | 2011-2026 | |
| 2 | José Prieto# | 10 | 2030-2042 | |
| 3 | Pedro Garza | 9 | 2025-2034 | |
| 3 | Raúl Pacheco | 9 | 2025-2038 | |
| 3 | Félix Villalobas# | 9 | 2024-2042 | |
| 6 | Carlos Cosme# | 8 | 2029-2042 | |
| 6 | António Lima# | 8 | 2029-2042 | |
| 6 | Sergio López | 8 | 2016-2026 | |
| 6 | Héctor Pérez | 8 | 2011-2031 | |
| 6 | José Pérez# | 8 | 2028-2042 | |
| 11 | Rafael Diéguez# | 7 | 2025-2042 | |
| 11 | Carlos Flores# | 7 | 2030-2042 | |
| 11 | Álex Martínez | 7 | 2009-2017 | |
| 11 | Sergio Pinzón# | 7 | 2029-2042 | |
| 11 | Luis Robles# | 7 | 2030-2041 | |
| 11 | Ángel Rodríguez# | 7 | 2032-2042 | |
| 17 | José Bernal# | 6 | 2032-2042 | |
| 17 | David Bienavides# | 6 | 2031-2041 | |
| 17 | Tomás Costa | 6 | 2007-2021 | |
| 17 | Javier Ferreira# | 6 | 2039-2042 | |
| 17 | César López | 6 | 2028-2034 | |
| 17 | Ricardo Martínez | 6 | 2027-2034 | |
| 17 | António Salazar# | 6 | 2037-2042 | |
| 17 | César Soto | 6 | 2015-2030 | |
| 17 | Harry Sullivan | 6 | 2011-2012 | |
| 26 | Tony Alvarado# | 5 | 2037-2042 | |
| 26 | Ricardo Encarnación# | 5 | 2039-2042 | |
| 26 | Tomás Figueroa# | 5 | 2033-2042 | |
| 26 | Arthur Graham | 5 | 2013-2018 | |
| 26 | Xavier Gómez# | 5 | 2033-2042 | |
| 26 | David Hernández | 5 | 2008-2013 | |
| 26 | Carlos Martínez# | 5 | 2033-2042 | |
| 26 | Jesús Muñóz# | 5 | 2026-2042 | |
| 26 | Jorge Ruíz | 5 | 2009-2029 | |
| 26 | Martín Silva | 5 | 2025-2039 | |
| 26 | José Torres# | 5 | 2022-2042 | |
| 37 | Claudio Acevedo | 4 | 2026-2033 | |
| 37 | Santiago Benítez# | 4 | 2028-2042 | |
| 37 | Carlos Domínguez# | 4 | 2027-2042 | |
| 37 | Félix García# | 4 | 2032-2042 | |
| 37 | Norm Hawk | 4 | 2007-2013 | |
| 37 | Lorenzo Herrera | 4 | 2009-2011 | |
| 37 | Esteban Martínez | 4 | 2028-2036 | |
| 37 | Mario Martínez | 4 | 2007-2018 | |
| 37 | Luis Mendoza# | 4 | 2033-2042 | |
| 37 | Mario Mendoza | 4 | 2007-2017 | |
| 37 | Jesús Mireles# | 4 | 2030-2042 | |
| 37 | Carlos Moreno | 4 | 2007-2012 | |
| 37 | Manuel Muñóz# | 4 | 2027-2042 | |
| 37 | Jesús Pedilla# | 4 | 2029-2042 | |
| 37 | Diego Quiñones# | 4 | 2033-2042 | |
| 37 | Júlio Ramos# | 4 | 2033-2042 | |
| 37 | Pedro Ruíz# | 4 | 2036-2042 | |
| 37 | Hideki Takahashi | 4 | 2010-2016 | |
| 37 | Ramón Torres# | 4 | 2029-2042 | |
| 37 | Ramón Villalobos# | 4 | 2028-2042 | |
| 57 | Julián Alaniz# | 3 | 2029-2042 | |
| 57 | Ángel Alemán | 3 | 2007-2010 | |
| 57 | Manuel Arroyo | 3 | 2015-2036 | |
| 57 | Pedro Barrón | 3 | 2007-2017 | |
| 57 | Carlos Camacho | 3 | 2020-2021 | |
| 57 | Juan Cardenas | 3 | 2012-2030 | |
| 57 | Augusto Cervantes | 3 | 2016-2030 | |
| 57 | Pedro Chávez | 3 | 2007-2023 | |
| 57 | Anthony Cox | 3 | 2013-2013 | |
| 57 | Cristián Delanoval# | 3 | 2030-2042 | |
| 57 | Ronald Dennis | 3 | 2008-2015 | |
| 57 | António Flores# | 3 | 2028-2042 | |
| 57 | Alberto Guerra# | 3 | 2030-2042 | |
| 57 | Juan Hernández# | 3 | 2038-2042 | |
| 57 | Carlos López# | 3 | 2029-2042 | |
| 57 | Víctor Meléndez# | 3 | 2031-2042 | |
| 57 | Zander Miller | 3 | 2013-2016 | |
| 57 | Ignacio Montoya# | 3 | 2032-2042 | |
| 57 | Jiro Nakamura | 3 | 2008-2010 | |
| 57 | Jaime Ortíz | 3 | 2011-2016 | |
| 57 | Carlos Pérez | 3 | 2008-2009 | |
| 57 | Manuel Ramírez | 3 | 2007-2014 | |
| 57 | Raúl Randín | 3 | 2007-2016 | |
| 57 | António Rodríguez# | 3 | 2027-2042 | |
| 57 | José Roldán | 3 | 2007-2009 | |
| 57 | Brian Ryan | 3 | 2019-2020 | |
| 57 | Alejandro Soto# | 3 | 2037-2042 | |
| 57 | Luis Sánchez | 3 | 2017-2023 | |
| 57 | Armando Tapia | 3 | 2007-2012 | |
| 86 | Alonso Apodaca | 2 | 2007-2017 | |
| 86 | António Ayala | 2 | 2027-2034 | |
| 86 | Jaime Camacho | 2 | 2015-2024 | |
| 86 | Raúl Chávez | 2 | 2010-2010 | |
| 86 | Félix Concepción# | 2 | 2034-2041 | |
| 86 | Cristián Contreras | 2 | 2036-2037 | |
| 86 | José Contreras | 2 | 2019-2020 | |
| 86 | António Cruz | 2 | 2015-2017 | |
| 86 | Ralph Dean | 2 | 2010-2013 | |
| 86 | Jason Doyle | 2 | 2008-2013 | |
| 86 | Carlos Feliciano | 2 | 2012-2014 | |
| 86 | José Flores# | 2 | 2040-2042 | |
| 86 | Juan Flores# | 2 | 2025-2042 | |
| 86 | Israel Franco | 2 | 2007-2018 | |
| 86 | Jorge Gallegos | 2 | 2010-2012 |
