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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jorge Ruíz# | 787 | 2025-2042 | |
| 2 | José Rosas | 373 | 2015-2030 | |
| 3 | Carlos Gonzáles# | 323 | 2028-2042 | |
| 4 | Luis Miguel Adron# | 200 | 2031-2042 | |
| 5 | Vicente Sáenz# | 146 | 2029-2042 | |
| 6 | Francisco Martínez | 116 | 2028-2038 | |
| 7 | Miguel Soto | 113 | 2015-2026 | |
| 8 | Carlos Colón | 108 | 2007-2012 | |
| 9 | Marcos Disdier | 92 | 2007-2012 | |
| 10 | Enrique Beltrán# | 91 | 2031-2042 | |
| 11 | Salvador Reyes | 90 | 2007-2020 | |
| 12 | Roberto Orralde# | 88 | 2030-2042 | |
| 13 | Juan Sánchez# | 83 | 2030-2042 | |
| 14 | Carlos Lima# | 81 | 2039-2042 | |
| 15 | Juan Jose Montoya# | 75 | 2024-2042 | |
| 16 | Augusto Patrio# | 60 | 2032-2042 | |
| 17 | Manny Gonzáles# | 57 | 2028-2042 | |
| 18 | Carlos Paredes# | 55 | 2035-2042 | |
| 19 | Sergio García | 51 | 2009-2017 | |
| 20 | Ángel Rivera# | 49 | 2035-2042 | |
| 21 | Gustavo Román | 48 | 2008-2008 | |
| 21 | Reynaldo Sánchez | 48 | 2016-2028 | |
| 23 | Pablo Souza | 44 | 2017-2028 | |
| 24 | Enrico Cruz# | 40 | 2036-2042 | |
| 25 | Luis Cruz# | 37 | 2017-2042 | |
| 26 | Orlando González# | 36 | 2041-2042 | |
| 27 | António Rivera# | 35 | 2034-2041 | |
| 28 | Cristián Quiñones | 34 | 2010-2027 | |
| 28 | Miguel Valenzuela# | 34 | 2039-2042 | |
| 30 | Alfredo Domínguez# | 33 | 2037-2042 | |
| 30 | Lorenzo Venegas# | 33 | 2036-2042 | |
| 32 | Mario Ortega# | 32 | 2030-2042 | |
| 33 | Júlio Chávez# | 30 | 2028-2042 | |
| 34 | Narahiko Nakamura | 28 | 2008-2008 | |
| 34 | José Pérez | 28 | 2007-2010 | |
| 36 | António Flores# | 27 | 2032-2042 | |
| 36 | Domingo López | 27 | 2029-2035 | |
| 38 | Alfonso Durango | 26 | 2007-2023 | |
| 38 | Juan Torres | 26 | 2008-2008 | |
| 40 | Wilson Gómez# | 24 | 2032-2042 | |
| 40 | Roberto Torres# | 24 | 2031-2042 | |
| 42 | Jorge Alemán | 22 | 2007-2011 | |
| 43 | Juan Reyes# | 20 | 2035-2042 | |
| 43 | Luis Salazar# | 20 | 2035-2042 | |
| 45 | José Gonzáles# | 16 | 2040-2042 | |
| 45 | Israel Mecías# | 16 | 2038-2042 | |
| 45 | Miguel Morán# | 16 | 2039-2042 | |
| 48 | Alonso Peña# | 14 | 2038-2042 | |
| 49 | Jeff Manning | 13 | 2008-2008 | |
| 50 | Rubén Arredondo# | 12 | 2037-2042 | |
| 50 | Chih-tui Xú# | 12 | 2036-2042 | |
| 52 | Ángel Alvarado | 10 | 2007-2010 | |
| 52 | Carlos Castro# | 10 | 2039-2042 | |
| 52 | Rubén Guillén | 10 | 2011-2019 | |
| 52 | Carlos López# | 10 | 2018-2042 | |
| 52 | Raúl Salinas# | 10 | 2035-2042 | |
| 57 | Nelson Herrera# | 9 | 2037-2042 | |
| 57 | Bartolo Muñóz | 9 | 2007-2016 | |
| 57 | Cisco Valle# | 9 | 2030-2042 | |
| 60 | Enrique Herrera | 8 | 2007-2024 | |
| 60 | Valentín Ramos# | 8 | 2040-2042 | |
| 60 | Takahiro Yoshida | 8 | 2007-2008 | |
| 63 | Ramón Fuentes# | 6 | 2040-2042 | |
| 63 | Pedro Gallegos# | 6 | 2038-2042 | |
| 63 | Yoshida Hasegawa | 6 | 2008-2008 | |
| 63 | Cisco Ochoa# | 6 | 2037-2042 | |
| 63 | Alonso Ruíz# | 6 | 2040-2042 | |
| 68 | Toin Sugiyama | 5 | 2008-2011 | |
| 68 | Ramón Vela# | 5 | 2033-2042 | |
| 68 | César Árias# | 5 | 2042-2042 | |
| 71 | Paco Cuellar | 4 | 2007-2013 | |
| 71 | Juan De Jesús# | 4 | 2037-2040 | |
| 71 | Carlos Lucero# | 4 | 2039-2042 | |
| 71 | Roberto Reyna# | 4 | 2034-2041 | |
| 71 | Alfonso Rivera# | 4 | 2031-2042 | |
| 76 | Pedro Chávez# | 3 | 2040-2042 | |
| 76 | Gilberto Crespo# | 3 | 2040-2042 | |
| 76 | Jorge Ortíz | 3 | 2007-2014 | |
| 79 | José Codne# | 2 | 2029-2042 | |
| 79 | Alberto Cortéz | 2 | 2008-2008 | |
| 79 | Miguel Angel Díaz | 2 | 2007-2014 | |
| 79 | Manuel García# | 2 | 2036-2042 | |
| 79 | Salvador Mejía | 2 | 2008-2009 | |
| 79 | António Rodríguez# | 2 | 2033-2040 | |
| 79 | Roberto Torres# | 2 | 2034-2040 | |
| 79 | Roberto Yánez# | 2 | 2030-2041 | |
| 87 | Ramón Gallardo# | 1 | 2040-2040 | |
| 87 | Ricardo García# | 1 | 2036-2041 | |
| 87 | Raúl Hinojosa# | 1 | 2042-2042 | |
| 87 | Miguel Romero# | 1 | 2038-2042 | |
| 87 | Raúl Sánchez | 1 | 2033-2041 | |
| 87 | Ricardo Terrero# | 1 | 2040-2040 | |
| 93 | Salvador Alvarado# | 0 | 2031-2042 | |
| 93 | Jesús Correa# | 0 | 2034-2042 | |
| 93 | Alonso Cruz# | 0 | 2037-2038 | |
| 93 | Fernando Cruz# | 0 | 2035-2042 | |
| 93 | Ramón De Andrés# | 0 | 2030-2038 | |
| 93 | Miguel Deleón# | 0 | 2033-2042 | |
| 93 | Anastasio Días | 0 | 2007-2026 | |
| 93 | Jesús Díaz# | 0 | 2035-2040 |
