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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Héctor Pérez | 239 | 2011-2031 | |
| 2 | Manny Flores# | 231 | 2027-2042 | |
| 3 | António Rodríguez# | 212 | 2027-2042 | |
| 4 | Félix Villalobas# | 204 | 2024-2042 | |
| 5 | Manuel Muñóz# | 199 | 2027-2042 | |
| 6 | Manuel Arroyo | 198 | 2015-2036 | |
| 7 | Juan Castillo# | 190 | 2026-2042 | |
| 8 | Martín Silva | 189 | 2025-2039 | |
| 9 | José Pérez# | 187 | 2028-2042 | |
| 10 | Raúl Pacheco | 177 | 2025-2038 | |
| 11 | Carlos Rivera# | 175 | 2029-2042 | |
| 12 | Jesús Muñóz# | 173 | 2026-2042 | |
| 13 | Félix López# | 168 | 2027-2042 | |
| 14 | Sergio López | 165 | 2016-2026 | |
| 14 | Ricardo Martínez | 165 | 2027-2034 | |
| 16 | Francisco Aguilar# | 164 | 2032-2042 | |
| 17 | Carlos Cosme# | 162 | 2029-2042 | |
| 17 | Ramón Días# | 162 | 2030-2042 | |
| 19 | Carlos Domínguez# | 161 | 2027-2042 | |
| 20 | Bernardo Sánchez# | 156 | 2030-2042 | |
| 21 | Tomás Costa | 153 | 2007-2021 | |
| 22 | Julián Alaniz# | 151 | 2029-2042 | |
| 22 | Pedro Ramírez# | 151 | 2027-2042 | |
| 24 | António Flores# | 149 | 2028-2042 | |
| 24 | Javier Sousa | 149 | 2011-2021 | |
| 26 | José Campos# | 147 | 2030-2042 | |
| 26 | Carlos Flores# | 147 | 2030-2042 | |
| 28 | Rafael Diéguez# | 146 | 2025-2042 | |
| 28 | Pedro Garza | 146 | 2025-2034 | |
| 30 | Jesús Núñez | 141 | 2015-2026 | |
| 31 | Arturo García | 138 | 2007-2023 | |
| 31 | Pedro Reyes | 138 | 2025-2040 | |
| 33 | Juan Cardenas | 136 | 2012-2030 | |
| 33 | Rodrigo Hernández# | 136 | 2031-2042 | |
| 35 | Ramón Villalobos# | 135 | 2028-2042 | |
| 36 | Jorge Ruíz | 133 | 2009-2029 | |
| 37 | António Lima# | 131 | 2029-2042 | |
| 37 | José Prieto# | 131 | 2030-2042 | |
| 39 | Carlos López# | 130 | 2029-2042 | |
| 40 | Manny Ríos# | 129 | 2030-2042 | |
| 41 | Víctor Meléndez# | 127 | 2031-2042 | |
| 42 | Alberto Guerra# | 126 | 2030-2042 | |
| 43 | Sergio Pinzón# | 124 | 2029-2042 | |
| 44 | Rafael Ramírez | 122 | 2017-2030 | |
| 45 | Roberto Alonaso# | 121 | 2030-2042 | |
| 46 | Víctor Rodeco# | 120 | 2028-2042 | |
| 47 | Roberto Cruz | 118 | 2023-2029 | |
| 48 | Juan Gamboa | 114 | 2022-2038 | |
| 49 | Cipriano Baca | 112 | 2018-2027 | |
| 49 | César Meléndez# | 112 | 2034-2042 | |
| 51 | David Bienavides# | 110 | 2031-2041 | |
| 52 | Ramón Torres# | 109 | 2029-2042 | |
| 53 | José Bernal# | 108 | 2032-2042 | |
| 54 | Arturo Acevedo# | 107 | 2030-2034 | |
| 54 | Félix Martínez | 107 | 2007-2015 | |
| 56 | Pedro Chávez | 106 | 2007-2023 | |
| 57 | Oliver Morales | 105 | 2021-2030 | |
| 58 | Salvador Martínez# | 103 | 2032-2041 | |
| 59 | Luis Farías# | 102 | 2030-2042 | |
| 60 | Arturo Luna# | 101 | 2029-2042 | |
| 61 | Israel Villarreal | 99 | 2007-2018 | |
| 62 | Juan Cora# | 98 | 2030-2042 | |
| 63 | Carlos Martínez# | 97 | 2033-2042 | |
| 64 | Cristián Delanoval# | 96 | 2030-2042 | |
| 64 | Héctor Molina# | 96 | 2031-2042 | |
| 64 | Manuel Ramírez | 96 | 2007-2014 | |
| 67 | Juan Barrón# | 95 | 2030-2042 | |
| 67 | Martín Gómez# | 95 | 2028-2042 | |
| 67 | Diego Quiñones# | 95 | 2033-2042 | |
| 70 | Cisco Salgado | 94 | 2007-2012 | |
| 70 | Armando Tapia | 94 | 2007-2012 | |
| 72 | Raúl Randín | 93 | 2007-2016 | |
| 72 | Juan Rodríguez# | 93 | 2024-2042 | |
| 72 | Vincente Rosário# | 93 | 2031-2041 | |
| 72 | Júlio Torres | 93 | 2022-2028 | |
| 76 | Juan Castro | 92 | 2013-2040 | |
| 76 | Xavier Gómez# | 92 | 2033-2042 | |
| 76 | Mario Mendoza | 92 | 2007-2017 | |
| 76 | Júlio Ramos# | 92 | 2033-2042 | |
| 76 | Bernardo Vigil# | 92 | 2026-2041 | |
| 81 | Luis Ramos | 90 | 2011-2026 | |
| 82 | Raúl Reyes# | 88 | 2030-2042 | |
| 82 | Eduardo Romano | 88 | 2011-2021 | |
| 84 | António Pérez# | 87 | 2032-2042 | |
| 84 | Pedro Ramírez | 87 | 2007-2011 | |
| 86 | César Soto | 86 | 2015-2030 | |
| 87 | Victor Hall | 85 | 2016-2021 | |
| 87 | Diego Rúbio | 85 | 2022-2030 | |
| 89 | Augusto Espinoza | 84 | 2007-2014 | |
| 89 | Alfonso Martínez | 84 | 2020-2025 | |
| 91 | Vincente Durán | 82 | 2019-2033 | |
| 92 | Augusto Cervantes | 81 | 2016-2030 | |
| 93 | Ángel Rodríguez# | 80 | 2032-2042 | |
| 93 | Roberto Serrano# | 80 | 2026-2041 | |
| 95 | Mario Hernández | 78 | 2007-2015 | |
| 95 | Valentim Ornelas | 78 | 2015-2021 | |
| 95 | Félix Ramírez# | 78 | 2033-2042 | |
| 98 | Esteban Martínez | 77 | 2028-2036 | |
| 98 | Jesús Mireles# | 77 | 2030-2042 | |
| 100 | Tillmão Biolley | 76 | 2008-2012 |
