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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Bartolo Mora# | 35 | 2025-2042 | |
| 2 | Pedro Flores# | 29 | 2024-2041 | |
| 3 | Francisco Cabrera# | 26 | 2035-2042 | |
| 4 | Mike Britt | 24 | 2016-2033 | |
| 4 | António Santos# | 24 | 2027-2042 | |
| 6 | Germán Hernández* | 23 | 2021-2034 | |
| 6 | Jerry Long | 23 | 2022-2033 | |
| 6 | Vito van Wondel# | 23 | 2032-2042 | |
| 9 | Danny Burton* | 22 | 2021-2038 | |
| 9 | John Pulsifer# | 22 | 2030-2042 | |
| 9 | Jarrod Ricks | 22 | 2018-2033 | |
| 12 | Wilson Muñóz | 21 | 2019-2036 | |
| 13 | Ricardo Mateo# | 20 | 2028-2042 | |
| 13 | Rob Raines* | 20 | 2010-2029 | |
| 13 | Marcos Sánchez# | 20 | 2020-2042 | |
| 13 | Sok-man Yi | 20 | 2010-2019 | |
| 17 | Pedro Rodríguez# | 19 | 2021-2042 | |
| 17 | Ramiro Salinas# | 19 | 2027-2042 | |
| 19 | Harley Schneider | 17 | 2023-2039 | |
| 20 | Rubén Cruz | 16 | 2007-2016 | |
| 20 | Francisco Lucador# | 16 | 2031-2042 | |
| 20 | Yoritomo Maeda# | 16 | 2032-2042 | |
| 20 | Raúl Medina | 16 | 2014-2028 | |
| 24 | Andrés Hernández* | 15 | 2021-2036 | |
| 24 | Ray Kimball | 15 | 2019-2033 | |
| 24 | Gordon Knopp# | 15 | 2032-2042 | |
| 24 | Tomás Martínez# | 15 | 2027-2042 | |
| 24 | Sean Peters | 15 | 2023-2037 | |
| 29 | Chris Allen | 14 | 2009-2022 | |
| 29 | Pedro Coronado# | 14 | 2032-2042 | |
| 29 | Claudio Hernández | 14 | 2028-2040 | |
| 29 | Don Mercer* | 14 | 2016-2033 | |
| 29 | Yosuke Morimoto# | 14 | 2030-2042 | |
| 29 | Decheng Wen | 14 | 2012-2023 | |
| 35 | William Petersen | 13 | 2010-2023 | |
| 35 | Félix Rodríguez# | 13 | 2026-2042 | |
| 37 | Pat Barry* | 12 | 2021-2039 | |
| 37 | Paul Carlisle | 12 | 2020-2034 | |
| 37 | Garry Charron# | 12 | 2026-2040 | |
| 37 | Dave Crocker | 12 | 2018-2030 | |
| 37 | Vern Duncan | 12 | 2023-2039 | |
| 37 | Gilberto Fernández# | 12 | 2031-2042 | |
| 37 | Matsusuke Hamada | 12 | 2021-2026 | |
| 37 | Tsumemasa Morimoto* | 12 | 2007-2022 | |
| 37 | Kevin Newton# | 12 | 2032-2042 | |
| 37 | Rob Woodard# | 12 | 2036-2042 | |
| 47 | Wilson Berry | 11 | 2007-2019 | |
| 47 | António Canseco# | 11 | 2031-2040 | |
| 47 | Jorge Martínez | 11 | 2018-2025 | |
| 47 | Bruce McGuire | 11 | 2022-2033 | |
| 47 | Juan Carlos Ornelza# | 11 | 2030-2042 | |
| 47 | Jeff Prat | 11 | 2022-2034 | |
| 47 | Claudio Pérez# | 11 | 2030-2042 | |
| 47 | Luis Torres | 11 | 2011-2022 | |
| 47 | Aaron Turner | 11 | 2007-2016 | |
| 56 | Yong-zhan Hu | 10 | 2009-2018 | |
| 56 | Guillermo Justavo | 10 | 2023-2034 | |
| 56 | José Luna | 10 | 2024-2037 | |
| 56 | Anthony Pace | 10 | 2007-2010 | |
| 56 | Augusto Quiñones | 10 | 2009-2016 | |
| 56 | Joe Riley# | 10 | 2031-2042 | |
| 56 | Francisco Rodríguez# | 10 | 2027-2042 | |
| 56 | Ryozo Takeuchi | 10 | 2020-2029 | |
| 56 | Rodrigo Vásquez# | 10 | 2030-2042 | |
| 56 | Chris Weaver | 10 | 2007-2016 | |
| 56 | Christian Webb | 10 | 2021-2039 | |
| 56 | Jeff Wilson | 10 | 2007-2021 | |
| 68 | Juan Aguilera# | 9 | 2037-2042 | |
| 68 | Santiago Aranda# | 9 | 2037-2042 | |
| 68 | Tony Carmona | 9 | 2016-2024 | |
| 68 | Luis Cedeño* | 9 | 2021-2039 | |
| 68 | Mark Collier | 9 | 2027-2033 | |
| 68 | Ramiro Fonseca | 9 | 2016-2026 | |
| 68 | Nick Giles | 9 | 2017-2026 | |
| 68 | Carlos Guerera | 9 | 2011-2022 | |
| 68 | Rod Johnson | 9 | 2015-2023 | |
| 68 | Ronald Lowry* | 9 | 2011-2025 | |
| 68 | Gustavo López | 9 | 2025-2038 | |
| 68 | Carlos Marino | 9 | 2026-2038 | |
| 68 | Eduardo Molina | 9 | 2007-2018 | |
| 68 | Jude Pew | 9 | 2007-2015 | |
| 68 | Cory Pierce | 9 | 2011-2022 | |
| 68 | Leonard Ramsey | 9 | 2016-2026 | |
| 68 | Nikolay Rusanovsky# | 9 | 2030-2040 | |
| 68 | Andy Sharp | 9 | 2022-2033 | |
| 68 | Augusto Valdéz | 9 | 2007-2013 | |
| 68 | Tony Velázquez | 9 | 2021-2038 | |
| 68 | Pat Watson# | 9 | 2024-2042 | |
| 68 | Chae-ku Yi | 9 | 2022-2031 | |
| 68 | Jin-song Zambrano# | 9 | 2035-2042 | |
| 91 | Lorenzo Amador | 8 | 2017-2029 | |
| 91 | Arthur Collins | 8 | 2015-2023 | |
| 91 | Armando Gandarilla | 8 | 2026-2040 | |
| 91 | Raúl García# | 8 | 2028-2040 | |
| 91 | Chris Holmes | 8 | 2010-2026 | |
| 91 | Anthony Hough | 8 | 2011-2023 | |
| 91 | Mauro Mata# | 8 | 2032-2042 | |
| 91 | Raúl Ortega# | 8 | 2025-2041 | |
| 91 | José Ríos# | 8 | 2035-2042 | |
| 91 | Raúl Uribe | 8 | 2023-2031 |
